Publications

* Equal contribution, ^§Co-corresponding

The developmental and genetic basis of male genitalia evolution in Drosophilids

Milton Urum and Ella Preger-Ben Noon

Current Opinion in Insect Science, Volume 68, 2025, 101335, DOI: https://doi.org/10.1016/j.cois.2025.101335

 

An i-motif-regulated enhancer, eRNA and adjacent lncRNA affect Lhb expression through distinct mechanisms in a sex-specific context

Tal Refael, Maya Sudman, Gil Golan, Lilach Pnueli, Sujay Naik, Ella Preger-Ben Noon, Arnon Henn, Ariel Kaplan, Philippa Melamed

Cell. Mol. Life Sci. 2024, 81, 361, DOI:https://doi.org/10.1007/s00018-024-05398-7

 

A developmental atlas of male terminalia across twelve species of Drosophila

Anna Urum*, Gavin Rice*, William Glassford, Yifat Yanku, Boris Shklyar, Mark Rebeiz^§, and Ella Preger-Ben Noon^§

Front. Cell Dev. Biol., 2024 12, DOI: https://doi.org/10.3389/fcell.2024.1349275

 

The density of regulatory information is a major determinant of evolutionary constraint on noncoding DNA in Drosophila

Gonzalo Sabarís, Daniela M Ortíz, Ian Laiker, Ignacio Mayansky, Sujay Naik, Giacomo Cavalli, David L Stern, Ella Preger-Ben Noon, and Nicolás Frankel

Mol Biol Evol, 2024 41(2): msae004, DOI: https://doi.org/10.1093/molbev/msae004

 

Developmental phenomics suggests that H3K4 monomethylation confers multi-level phenotypic robustness

Lautaro Gandara, Albert Tsai, Måns Ekelöf, Rafael Galupa, Ella Preger-Ben Noon, Theodore Alexandrov, Justin Crocker

Cell Reports, 2022 41(11): 111832, DOI: https://doi.org/10.1016/j.celrep.2022.111832

 

Can changes in 3D genome architecture create new regulatory landscapes that contribute to phenotypic evolution?

Ella Preger-Ben Noon^§ and Nicolás Frankel^§

Essays in Biochemistry, 2022, 66(6),745-752

 

delilah, prospero and D-Pax2 constitute a gene regulatory network essential for the development of functional proprioceptors

Adel Avetisyan, Yael Glatt, Maya Cohen, Yael Timerman, Nitay Aspis, Atalia Nachman, Naomi Halachmi, Ella Preger-Ben Noon^§ and Adi Salzberg^§

eLife. DOI: 10.7554/eLife.70833, December, 2021

 

A complex gene regulatory architecture underlies the development and evolution of cuticle morphology in Drosophila

Sebastian Kittelmann*, Ella Preger-Ben Noon*, Alistair P McGregor and Nicolás Frankel.

Current Opinion in Genetics & Development. 69:21-27, August, 2021

 

Actors with multiple roles: pleiotropic enhancers and the paradigm of enhancer modularity

Gonzalo Sabarís, Ian Laiker, Ella Preger-Ben Noon^§ and Nicolás Frankel^§.

Trends Genet. 35(6):423-433, June, 2019

 

Comprehensive analysis of a cis-regulatory region reveals pleiotropy in enhancer function.

Ella Preger-Ben Noon*, Gonzalo Sabarís*, Daniela M Ortiz, Jonathan Sager, Anna Liebowitz, David L Stern and Nicolás Frankel.

Cell Rep. 22(11):3021-3031, March 13, 2018

 

Evolved repression overcomes enhancer robustness.

Ella Preger-Ben Noon^§, Fred P Davis and David L Stern^§.

Dev. Cell. 39(5):572-584, December 5, 2016

 

The soft touch: low-affinity transcription factor binding sites in development and evolution.

Justin M Crocker*, Ella Preger-Ben Noon* and David L. Stern.

Current Topics in Developmental Biology. 117:455-469, 2016

 

Evolving genital structures: a deep look at network co-option.

Ella Preger-Ben Noon and Nicolás Frankel.

Dev. Cell. 34(5):485-486, September 14, 2015

 

Bi-functional cross-linking reagents efficiently capture protein-DNA complexes in Drosophila embryos.

Tsutomu Aoki, Daniel Wolle, Ella Preger-Ben Noon, Qi Dai, Eric C Lai and Paul Schedl.

Fly (Austin). 8(1):43-51, 2014

 

Comparative spatiotemporal analysis of Hox gene expression in early stages of intermediate mesoderm formation.

Hila Barak*, Ella Preger-Ben Noon* and Ram Reshef.

Dev. Dyn. 241(10):1637–1649, October, 2012

 

Interplay between Activin and Hox genes determine the formation of the kidney morphogenetic field.

Ella Preger-Ben Noon*, Hila Barak*, Noga Guttmann-Raviv and Ram Reshef.

Development. 136(12):1995-2004, May 22, 2009

 

The human sef-a isoform utilizes different mechanisms to regulate receptor tyrosine kinase signaling pathways and subsequent cell fate.

Inbal Ziv, Yaron Fuchs, Ella Preger, Ariel Shabtay, Haggar Hardu, Tal Zilpa, Naama Dym and Dina Ron.

JBC. 281(51):39225-39235, December 22, 2006

 

Alternative splicing generates an isoform of the human SEF gene with altered subcellular localization and specificity.

Ella Preger, Inbal Ziv, Ariel Shabtay, Ifat Sher, Michael Tsang, Igor B Dawid, Yael Altuvia and Dina Ron (2004)

PNAS. 101(5):1229-1234, February 4, 2004